RCC2 anticorps (AA 1-50)

N° du produit ABIN7452004

Cet anticorps Lapin Polyclonal détecte spécifiquement RCC2 dans WB et IP. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour RCC2 anticorps (AA 1-50) (ABIN7452004)

Antigène: RCC2 (Regulator of Chromosome Condensation 2 (RCC2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RCC2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-RCC2 anticorps

Épitope: AA 1-50

Fonction: Rabbit anti-RCC2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur RCC2

Antigène: RCC2 (Regulator of Chromosome Condensation 2 (RCC2))

Autre désignation: RCC2

Sujet: Background: RCC2 (regulator of chromosome condensation 2) is a member of the RCC1 family of guanine nucleotide exchange factors. RCC2 has been identified as part of the chromosomal passenger complex (CPC) which coordinates the chromosomal and cytoskeletal events of mitosis. Chromosomal passengers are proteins present in complexes with aurora B, inner centromeric protein (INCENP), survivin, and borealin. RCC2 has been demonstrated to be required for the recruitment of survivin and aurora B and is essential for proper chromosome segregation and the completion of cell cleavage. Loss of RCC2 inhibits spindle assembly, activates the spindle assembly checkpoint, and blocks cells in prometaphase.

ID gène: 55920

NCBI Accession: NP_061185

UniProt: Q9P258