TLK1 anticorps (AA 716-766)

N° du produit ABIN7452103

Cet anticorps Lapin Polyclonal détecte spécifiquement TLK1 dans WB et IP. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour TLK1 anticorps (AA 716-766) (ABIN7452103)

Antigène: TLK1 (Tousled-Like Kinase 1 (TLK1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLK1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-TLK1 anticorps

Épitope: AA 716-766

Fonction: Rabbit anti-TLK1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 716 and 766

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur TLK1

Antigène: TLK1 (Tousled-Like Kinase 1 (TLK1))

Autre désignation: TLK1

Sujet: Background: Tousled-like kinase 1 (TLK1) is a serine/threonine kinase involved in chromatin assembly and the DNA damage response. The tousled (Tsl) kinase was first identified in Arabidopsis thaliana and speculated to be involved in cell division during patterning of plant organs. There are two tousled-like kinases in humans, TLK1 and TLK2, that can dimerize or heterodimerize for function and can be phosphorylated and inactivated by Chk1 in response to DNA damage. The histone chaperone, Asf1 (anti-silencing function 1), has been reported as a substrate for both TLK1 and TLK2. TLK1 has also been shown to be important for cell cycle progression and proper chromosome segregation.

ID gène: 9874

NCBI Accession: NP_036422

UniProt: Q9UKI8