UFD1L anticorps (AA 257-307)

N° du produit ABIN7452140

L’anticorps anti-UFD1L Polyclonal Lapin est utilisé pour la détection de UFD1L dans des échantillons de Humain. Il a été validé pour WB et IP.

Aperçu rapide pour UFD1L anticorps (AA 257-307) (ABIN7452140)

Antigène: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UFD1L est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-UFD1L anticorps

Épitope: AA 257-307

Fonction: Rabbit anti-UFD1 Antibody, Affinity Purified

Homologie: Mouse,Rat

Purification: Affinity Purified

Immunogène: between AA 257 and 307

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur UFD1L

Antigène: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Autre désignation: UFD1

Sujet: Background: Ubiquitin fusion degradation protein 1 homolog (UFD1) forms a dimer with Npl4 (nuclear protein localization 4) and can associate with the ATPase, p97/VCP, to form a ternary complex involved in the ubiquitin-proteasome pathway. The UFD1-p97-Npl4 complex functions to recognize ubiquitin-tagged proteins and facilitate their presentation to the 26S proteasome for degradation. This ternary complex has also been shown to play an important role in mitotic spindle disassembly. Hemizygosity in the gene which encodes UFD1 (UFD1L) is the cause of some catch 22-associated developmental defects. Additionally, the UFD1L gene has also been implicated in the neurodevelopment al origin of schizophrenia.

ID gène: 7353

NCBI Accession: NP_005650

UniProt: Q92890