EYA3 anticorps (AA 30-60)
Aperçu rapide pour EYA3 anticorps (AA 30-60) (ABIN7452325)
Antigène
Voir toutes EYA3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 30-60
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Fonction
- Rabbit anti-EYA3 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- between AA 30 and 60
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Isotype
- IgG
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Indications d'application
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-EYA3 antibody ABIN7453703.
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- EYA3 (Eyes Absent Homolog 3 (EYA3))
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Autre désignation
- EYA3
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Sujet
- Background: EYA3 (eyes absent homolog 3) functions as a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). EYA3 promotes efficient DNA repair by dephosphorylating H2AX and promoting the recruitment of DNA repair complexes containing MDC1. EYA3 coactivates SIX1. Together with SIX1 and DACH2 EYA3 seems to be involved in myogenesis. EYA3 may be involved in development of the eye [taken from the Universal Protein Resource (UniProt) Q99504].
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ID gène
- 2140
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NCBI Accession
- NP_001981
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UniProt
- Q99504
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Pathways
- Positive Regulation of Response to DNA Damage Stimulus
Antigène
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