FIP200 anticorps (AA 250-300)

N° du produit ABIN7452328

Cet anticorps Lapin Polyclonal détecte spécifiquement FIP200 dans IP. Il présente une réactivité envers Humain.

Aperçu rapide pour FIP200 anticorps (AA 250-300) (ABIN7452328)

Antigène: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FIP200 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-FIP200 anticorps

Épitope: AA 250-300

Fonction: Rabbit anti-FIP200/RB1CC1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 250 and 300

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-FIP200/RB1CC1 antibody ABIN7451783.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur FIP200

Antigène: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Autre désignation: FIP200/RB1CC1

Sujet: Background: FIP200 (FAK-family interacting protein of 200 kDa) appears to play several key roles related to cell growth, proliferation, development, and tumorigenesis. FIP200 was originally identified in a yeast two-hybrid screen for Pyk2 kinase interacting proteins. It was later identified as a protein that interacts with FAK (focal adhesion kinase), a signal transducing protein that mediates signals from the extracellular matrix to the cytoskeleton to influence cell motility, and cell cycle progression. FIP200 is also known as RB1CC1 (RB1-inducible coiled-coil 1) and has been found to function as a regulator of the retinoblastoma 1 (RB1) tumor suppressor. FIP200 associates with the tumor suppressor TSC1 which partners with TSC2 to antagonize the mTOR signaling pathway. FIP200 association with TSC2 promotes mTOR activity by interfering with the antagonistic effects of the TSC1-TSC2 complex.

ID gène: 9821

NCBI Accession: NP_055596

UniProt: Q8TDY2

Pathways: Regulation of Cell Size, Autophagy