NUMB anticorps (AA 525-575)

N° du produit ABIN7452379

Cet anticorps Lapin Polyclonal détecte spécifiquement NUMB dans IP. Il présente une réactivité envers Humain.

Aperçu rapide pour NUMB anticorps (AA 525-575) (ABIN7452379)

Antigène: NUMB (Numb Homolog (NUMB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUMB est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-NUMB anticorps

Épitope: AA 525-575

Fonction: Rabbit anti-NUMB Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 525 and 575

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-NUMB antibody ABIN7451903.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NUMB

Antigène: NUMB (Numb Homolog (NUMB))

Autre désignation: NUMB

Sujet: Background: NUMB plays an essential role in the determination of cell fate and development and appears to be especially important to sensory organogenesis and neurogenesis. NUMB is a notch1-interacting protein that antagonizes the notch1 signaling pathway. In the cell, NUMB is asymmetrically localized. The polarized distribution of NUMB in the cell is fundamental to its function of promoting asymmetric cell division for cell fate specification. Numb is also implicated to function as an endocytic protein, as it interacts with EPS15, a protein involved in endocytosis.

ID gène: 8650

NCBI Accession: NP_001005743

UniProt: P49757

Pathways: Cell-Cell Junction Organization