SMN1 anticorps (AA 50-100)

N° du produit ABIN7452436

Cet anticorps Lapin Polyclonal détecte spécifiquement SMN1 dans IP. Il présente une réactivité envers Humain.

Aperçu rapide pour SMN1 anticorps (AA 50-100) (ABIN7452436)

Antigène: SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMN1 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-SMN1 anticorps

Épitope: AA 50-100

Fonction: Rabbit anti-SMN1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 50 and 100

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-SMN1 antibody ABIN7452052.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SMN1

Antigène: SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))

Autre désignation: SMN1

Sujet: Background: Survival motor neuron protein (SMN1) has been identified as the gene that is defective in spinal muscular atrophy (SMA), a neurodegenerative autosomal recessive disease characterized by paralysis and muscular atrophy which results from the loss of motor neurons in the spinal cord. There are two closely related SMN genes that do not appear to be functionally redundant. SMN1 represents the telomeric copy while SMN2 represents the centromeric copy. In the cell, SMN1 is part of a large complex of proteins involved in snRNP biogenesis. The functional role of SMN1 is proposed to play a role in messenger and ribosomal RNA transcription and processing.

ID gène: 6606

NCBI Accession: NP_000335

UniProt: Q16637

Pathways: Ribonucleoprotein Complex Subunit Organization