USP1 anticorps (AA 300-350)

N° du produit ABIN7452550

Cet anticorps Lapin Polyclonal détecte spécifiquement USP1 dans IP. Il présente une réactivité envers Humain.

Aperçu rapide pour USP1 anticorps (AA 300-350) (ABIN7452550)

Antigène: USP1 (Ubiquitin Specific Peptidase 1 (USP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP1 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-USP1 anticorps

Épitope: AA 300-350

Fonction: Rabbit anti-USP1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 300 and 350

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur USP1

Antigène: USP1 (Ubiquitin Specific Peptidase 1 (USP1))

Autre désignation: USP1

Sujet: Background: Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 1 (USP1) has been found to play a role in the Fanconi anemia DNA repair pathway. USP1 specifically removes monoubiquitination from the Fanconi anemia D2 (FANCD2) protein and from the proliferating cell nuclear antigen (PCNA). Deubiquitination of FANCD2 and PCNA is critical to their role in the DNA damage response and DNA crosslink repair.

ID gène: 7398

NCBI Accession: NP_003359

UniProt: O94782