KIAA1524 anticorps (N-Term)

N° du produit ABIN7452647

L’anticorps Souris Monoclonal anti-KIAA1524 a été validé pour WB et IP. Il convient pour détecter KIAA1524 dans des échantillons de Humain et Souris.

Aperçu rapide pour KIAA1524 anticorps (N-Term) (ABIN7452647)

Antigène: KIAA1524

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KIAA1524 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 2A1-9A4

Détail du produit anti-KIAA1524 anticorps

Épitope: N-Term

Fonction: Mouse anti-CIP2A Monoclonal Antibody, Affinity Purified [2A1-9A4]

Purification: Affinity Purified

Immunogène: Amino terminal one-third of the CIP2A (GeneID 57650) recombinant protein

Isotype: IgG

Information d'application

Indications d'application:

IP: 20 μL/mg lysate

WB: 17:40:00

Restrictions: For Research Use only

Stockage

Concentration: 40 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur KIAA1524

Antigène: KIAA1524

Autre désignation: CIP2A

Sujet: Background: CIP2A (cancerous inhibitor of PP2A) was originally identified as p90, a cytoplasmic autoantigen found in the serum from a cancer patient. It was later described as a protein that interacted with the c-myc oncogene and functioned as an inhibitor of protein phosphatase 2A (PP2A) activity. Inhibition of PP2A phosphatase activity by CIP2A prevents c-myc phosphorylation and counteracts c-myc proteolytic degradation, thereby stabilizing c-myc and promoting cell growth and transformation. CIP2A is found to be overexpressed in some human malignancies and is thus classified as an oncogene that may be an important contributor to tumor formation.

ID gène: 57650

NCBI Accession: NP_065941

UniProt: Q8TCG1