KIAA1524 anticorps (N-Term)

N° du produit ABIN7452647

Détail du produit anti-KIAA1524 anticorps

Antigène: KIAA1524

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KIAA1524 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Mouse anti-CIP2A Monoclonal Antibody, Affinity Purified [2A1-9A4]

Purification: Affinity Purified

Immunogène: Amino terminal one-third of the CIP2A (GeneID 57650) recombinant protein

Clone: 2A1-9A4

Isotype: IgG

Information d'application

Indications d'application:

IP: 20 μL/mg lysate

WB: 17:40:00

Restrictions: For Research Use only

Stockage

Concentration: 40 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur KIAA1524

Antigène: KIAA1524

Autre désignation: CIP2A (KIAA1524 Produits)

Synonymes: anticorps CIP2A, anticorps p90, anticorps AA408511, anticorps AU018569, anticorps Cip2a, anticorps Kiaa1524, anticorps KIAA1524, anticorps LOC100222895, anticorps RGD1310335, anticorps cell proliferation regulating inhibitor of protein phosphatase 2A, anticorps RIKEN cDNA C330027C09 gene, anticorps KIAA1524, anticorps cell proliferation regulating inhibitor of protein phosphatase 2A L homeolog, anticorps CONSTANS interacting protein 2a, anticorps CIP2A, anticorps C330027C09Rik, anticorps KIAA1524, anticorps cip2a.L, anticorps CIP2a, anticorps cip2a, anticorps Cip2a

Sujet: Background: CIP2A (cancerous inhibitor of PP2A) was originally identified as p90, a cytoplasmic autoantigen found in the serum from a cancer patient. It was later described as a protein that interacted with the c-myc oncogene and functioned as an inhibitor of protein phosphatase 2A (PP2A) activity. Inhibition of PP2A phosphatase activity by CIP2A prevents c-myc phosphorylation and counteracts c-myc proteolytic degradation, thereby stabilizing c-myc and promoting cell growth and transformation. CIP2A is found to be overexpressed in some human malignancies and is thus classified as an oncogene that may be an important contributor to tumor formation.

ID gène: 57650

NCBI Accession: NP_065941

UniProt: Q8TCG1