C17ORF85 anticorps (AA 25-75)
Aperçu rapide pour C17ORF85 anticorps (AA 25-75) (ABIN7452805)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 25-75
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Fonction
- Rabbit anti-C17orf85 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- between AA 25 and 75
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Isotype
- IgG
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Indications d'application
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IP: 50-100 μL/mg lysate
WB: 1:10,000 - 1:25,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- C17ORF85 (Chromosome 17 Open Reading Frame 85 (C17ORF85))
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Autre désignation
- C17orf85
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Sujet
- Background: C17orf85 (NCBP3) associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. C17orf85 (NCBP3) serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with C17orf85 (NCBP3) does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the C17orf85 (NCBP3) activity is critical to inhibit virus growth. [taken from the Universal Protein Resource (UniProt) Q53F19].
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ID gène
- 55421
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UniProt
- Q53F19
Antigène
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