CCDC22 anticorps (AA 577-627)

N° du produit ABIN7452809

L’anticorps Lapin Polyclonal anti-CCDC22 a été validé pour WB et IP. Il convient pour détecter CCDC22 dans des échantillons de Humain et Souris.

Aperçu rapide pour CCDC22 anticorps (AA 577-627) (ABIN7452809)

Antigène: CCDC22 (Coiled-Coil Domain Containing 22 (CCDC22))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCDC22 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-CCDC22 anticorps

Épitope: AA 577-627

Fonction: Rabbit anti-CCDC22 Antibody, Affinity Purified

Homologie: Bovine

Purification: Affinity Purified

Immunogène: between AA 577 and 627

Isotype: IgG

Information d'application

Indications d'application:

IP: 50-100 μL/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CCDC22

Antigène: CCDC22 (Coiled-Coil Domain Containing 22 (CCDC22))

Autre désignation: CCDC22

Sujet: Background: CCDC22 is involved in regulation of NF-kappa-B signaling. Promotes ubiquitination of I-kappa-B-kinase subunit IKBKB and its subsequent proteasomal degradation leading to NF-kappa-B activation, the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. May down-regulate NF-kappa-B activity via association with COMMD1 and involving a CUL2-dependent E3 ubiquitin ligase complex. Regulates the cellular localization of COMM domain-containing proteins, such as COMMD1 and COMMD10. Plays a role in copper ion homeostasis. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery, the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes. [taken from the Universal Protein Resource (UniProt) O60826].

ID gène: 28952

UniProt: O60826