FKBP4 anticorps (AA 440-459)

N° du produit ABIN7452888

Cet anticorps anti-FKBP4 est un anticorps Lapin Polyclonal détectant FKBP4 dans WB. Adapté pour Humain et Souris.

Aperçu rapide pour FKBP4 anticorps (AA 440-459) (ABIN7452888)

Antigène: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FKBP4 anticorps

Épitope: AA 440-459

Fonction: Rabbit anti-FKBP4/FKBP52 Antibody, Affinity Purified

Homologie: Rabbit

Purification: Affinity Purified

Immunogène: between AA 440 and 459

Isotype: IgG

Information d'application

Indications d'application:

IP: Not recommended. Use rabbit anti-FKBP4/FKBP52 antibody A301-427A.

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur FKBP4

Antigène: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Autre désignation: FKBP4/FKBP52

Sujet: Background: FKBP4/FKBP52 is an immunophilin and target of FK506, a macrolide immunosuppressive drug derived from Streptomyces tsukubaensis. Like other FK506 binding proteins, FKBP52 exhibits peptidyl-prolyl cis-trans isomerase activity, but does not appear to mediate the immunosuppressive activities of FK506. The most studied role of FKBP4/FKBP52 surrounds its involvement in the regulation of steroid receptor signaling. In association with the molecular chaperone Hsp90, FKBP4/FKBP52 is able to influence steroid-hormone binding affinity and transcriptional activity.

ID gène: 2288

NCBI Accession: NP_002005

UniProt: Q02790

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway