EXOSC10 anticorps (AA 835-885)

N° du produit ABIN7452933

Cet anticorps anti-EXOSC10 est un anticorps Lapin Polyclonal détectant EXOSC10 dans WB. Adapté pour Humain.

Aperçu rapide pour EXOSC10 anticorps (AA 835-885) (ABIN7452933)

Antigène: EXOSC10 (Exosome Component 10 (EXOSC10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EXOSC10 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EXOSC10 anticorps

Épitope: AA 835-885

Fonction: Rabbit anti-EXOSC10 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 835 and 885

Isotype: IgG

Information d'application

Indications d'application:

IP: Not recommended

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur EXOSC10

Antigène: EXOSC10 (Exosome Component 10 (EXOSC10))

Autre désignation: EXOSC10

Sujet: Background: Exosome component 10 (EXOSC10) is a putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRN. It is also involved in the elimination of RNA-processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs [taken from the Universal Protein Resource (UniProt) Q01780].

ID gène: 5394

NCBI Accession: NP_001001998

UniProt: Q01780