Fibrillarin anticorps (AA 1-50)
Aperçu rapide pour Fibrillarin anticorps (AA 1-50) (ABIN7452936)
Antigène
Voir toutes Fibrillarin (FBL) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-50
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Fonction
- Rabbit anti-Fibrillarin Antibody, Affinity Purified
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Homologie
- Rat
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Purification
- Affinity Purified
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Immunogène
- Between AA 1 and 50
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Isotype
- IgG
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Indications d'application
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IP: Not recommended
WB: 1:1,000 - 1:5,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- Fibrillarin (FBL)
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Autre désignation
- Fibrillarin
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Sujet
- Background: Fibrillarin is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. Fibrillarin contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin [taken from NCBI Entrez Gene (Gene ID: 2091)].
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ID gène
- 2091
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NCBI Accession
- NP_001427
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UniProt
- P22087
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Pathways
- Ribonucleoside Biosynthetic Process
Antigène
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