PTRH2 anticorps (AA 129-179)

N° du produit ABIN7453173

Cet anticorps anti-PTRH2 est un anticorps Lapin Polyclonal détectant PTRH2 dans WB. Adapté pour Humain.

Aperçu rapide pour PTRH2 anticorps (AA 129-179) (ABIN7453173)

Antigène: PTRH2 (Peptidyl-tRNA Hydrolase 2 (PTRH2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTRH2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PTRH2 anticorps

Épitope: AA 129-179

Fonction: Rabbit anti-PTRH2/BIT1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 129 and 179

Isotype: IgG

Information d'application

Indications d'application:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PTRH2

Antigène: PTRH2 (Peptidyl-tRNA Hydrolase 2 (PTRH2))

Autre désignation: PTRH2/BIT1

Sujet: Background: Peptidyl-tRNA hydrolase 2 (PTRH2) is a mitochondrial protein with two putative domains, an N-terminal mitochondrial localization sequence, and a UPF0099 domain. In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, to release the peptidyl moiety from tRNA, thereby preventing the accumulation of dissociated peptidyl-tRNA that could reduce the efficiency of translation. This protein also plays a role regulating cell survival and death. It promotes survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix (ECM), but also promotes apoptosis in cells that have lost their attachment to the ECM, a process called anoikos [taken from NCBI Entrez Gene (Gene ID: 51651)].

ID gène: 51651

UniProt: Q9Y3E5