SUPT16H anticorps (AA 997-1047)

N° du produit ABIN7453210

Cet anticorps Lapin Polyclonal détecte spécifiquement SUPT16H dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour SUPT16H anticorps (AA 997-1047) (ABIN7453210)

Antigène: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUPT16H est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SUPT16H anticorps

Épitope: AA 997-1047

Fonction: Rabbit anti-Spt16 Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: between AA 997 and 1047

Isotype: IgG

Information d'application

Indications d'application:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SUPT16H

Antigène: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Autre désignation: Spt16

Sujet: Background: Spt16 is a Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is composed of two subunits: SSRP1 and Spt16. It is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, and then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II [taken from the Universal Protein Resource (UniProt) Q9Y5B9].

ID gène: 11198

NCBI Accession: NP_009123

UniProt: Q9Y5B9

Pathways: Chromatin Binding