ARVCF anticorps (AA 75-125)

N° du produit ABIN7453257

Cet anticorps anti-ARVCF est un anticorps Lapin Polyclonal détectant ARVCF dans WB. Adapté pour Humain.

Aperçu rapide pour ARVCF anticorps (AA 75-125) (ABIN7453257)

Antigène: ARVCF (Armadillo Repeat Gene Deleted in Velocardiofacial Syndrome (ARVCF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARVCF est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ARVCF anticorps

Épitope: AA 75-125

Fonction: Rabbit anti-ARVCF Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: between AA 75 and 125

Isotype: IgG

Information d'application

Indications d'application:

IP: Not recommended

WB: 1:500 - 1:2,500

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur ARVCF

Antigène: ARVCF (Armadillo Repeat Gene Deleted in Velocardiofacial Syndrome (ARVCF))

Autre désignation: ARVCF

Sujet: Background: Armadillo repeat gene deleted in velocardiofacial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein [taken from NCBI Entrez Gene (Gene ID: 421)].

ID gène: 421

NCBI Accession: NP_001661

UniProt: O00192