DCK anticorps (AA 210-260)

N° du produit ABIN7453430

L’anticorps Lapin Polyclonal anti-DCK a été validé pour WB, IP et IHC (fp). Il convient pour détecter DCK dans des échantillons de Humain et Souris.

Aperçu rapide pour DCK anticorps (AA 210-260) (ABIN7453430)

Antigène: DCK (Deoxycytidine Kinase (DCK))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCK est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-DCK anticorps

Épitope: AA 210-260

Fonction: Rabbit anti-DCK Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 210 and 260

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur DCK

Antigène: DCK (Deoxycytidine Kinase (DCK))

Autre désignation: DCK

Sujet: Background: Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivitiy [taken from NCBI Entrez Gene (Gene ID: 1633)].

ID gène: 1633

NCBI Accession: NP_000779

UniProt: P27707