TBL1XR1 anticorps (AA 100-150)

N° du produit ABIN7453451

L’anticorps Lapin Polyclonal anti-TBL1XR1 a été validé pour WB, IP et IHC (fp). Il convient pour détecter TBL1XR1 dans des échantillons de Humain et Souris.

Aperçu rapide pour TBL1XR1 anticorps (AA 100-150) (ABIN7453451)

Antigène: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBL1XR1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-TBL1XR1 anticorps

Épitope: AA 100-150

Fonction: Rabbit anti-TBLR1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 100 and 150

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur TBL1XR1

Antigène: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Autre désignation: TBLR1

Sujet: Background: TBLR1 is a six WD-40 repeat protein with high sequence homology to TBL1 (transducin beta-like protein 1) and is part of the SMRT (silencing mediator of retinoid and thyroid hormone receptors) and N-CoR (nuclear receptor corepressor) complexes that interact with nuclear receptors and repress transcription. Biochemical characterization of SMRT and N-CoR complexes demonstrate that SMRT and N-CoR are present in complexes that include HDAC3 (histone deacetylase 3), TBL1, and TBLR1. Association with HDAC3 indicates that these complexes may repress transcription through histone deacetylation and chromatin remodeling.

ID gène: 79718

NCBI Accession: NP_078941

UniProt: Q9BZK7

Pathways: Regulation of Lipid Metabolism by PPARalpha