NPAT anticorps (AA 1377-1427)

N° du produit ABIN7453485

Cet anticorps anti-NPAT est un anticorps Lapin Polyclonal détectant NPAT dans WB, IP et IHC (fp). Adapté pour Humain.

Aperçu rapide pour NPAT anticorps (AA 1377-1427) (ABIN7453485)

Antigène: NPAT (Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NPAT est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-NPAT anticorps

Épitope: AA 1377-1427

Fonction: Rabbit anti-NPAT Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: between AA 1377 and 1427

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NPAT

Antigène: NPAT (Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT))

Autre désignation: NPAT

Sujet: Background: NPAT (nuclear protein of the ataxia telangiectasia mutated locus) is required for progression through the G1 and S phases of the cell cycle and for S phase entry. It activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. NPAT also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q14207].

ID gène: 4863

NCBI Accession: NP_002510

UniProt: Q14207