Raly anticorps (AA 150-200)

N° du produit ABIN7453509

Détail du produit anti-Raly anticorps

Antigène: Raly (RALY) (RNA-binding protein Raly (RALY))

Épitope: AA 150-200

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Raly est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-RALY Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 150 and 200

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-RALY antibody A302-070A.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Raly

Antigène: Raly (RALY) (RNA-binding protein Raly (RALY))

Autre désignation: RALY (RALY Produits)

Synonymes: anticorps AI663842, anticorps Merc, anticorps HNRPCL2, anticorps P542, anticorps zgc:103445, anticorps hnRNP-associated with lethal yellow, anticorps RALY heterogeneous nuclear ribonucleoprotein, anticorps Raly, anticorps RALY, anticorps raly

Sujet: Background: The agouti (a) locus includes the mouse agouti gene that regulates coat color in mice by controlling the relative amount and distribution of yellow and black pigment in the coat hairs. A mutation in the agouti locus, lethal yellow (Ay), results in an all-yellow coat color along with a number of dominant pleiotropic effects such as obesity, diabetes, tumor susceptibility, and embryonic lethality in homozygotes. Molecular analysis of the Ay transcript revealed that the Ay transcript includes the coding region of the a gene but also included novel sequence. The novel sequence was found to originate from a 5'-noncoding exon of a gene that was named Raly, because it had the potential to encode an hnRNP protein that is associated with lethal yellow.

ID gène: 22913

NCBI Accession: NP_057951

UniProt: Q9UKM9