WDR77 anticorps (AA 1-50)

N° du produit ABIN7453513

Cet anticorps Lapin Polyclonal détecte spécifiquement WDR77 dans WB, IP et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour WDR77 anticorps (AA 1-50) (ABIN7453513)

Antigène: WDR77 (WD Repeat Domain 77 (WDR77))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WDR77 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-WDR77 anticorps

Épitope: AA 1-50

Fonction: Rabbit anti-WDR77/MEP50 Antibody, Affinity Purified

Homologie: Bovine,Orangutan

Purification: Affinity Purified

Immunogène: between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-WDR77/MEP50 antibody A301-562A.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur WDR77

Antigène: WDR77 (WD Repeat Domain 77 (WDR77))

Autre désignation: WDR77/MEP50

Sujet: Background: WDR77/MEP50 is a component of the methylosome, a large protein arginine methyltransferase complex that modifies specific arginines to dimethylarginines in splicesomal Sm proteins. WDR77/MEP50 associates with the methyltransferase JBP1 (PRMT5) and is important for methylosome activity. WDR77/MEP50 has also been shown to associate with the polycomb group protein, SUZ12, and histone H2A. In this context, WDR77/MEP50 is proposed to function as an adaptor between PRMT5 and its substrate H2A to regulate transcription.

ID gène: 79084

NCBI Accession: NP_077007

UniProt: Q9BQA1

Pathways: Ribonucleoprotein Complex Subunit Organization