PKD2 anticorps (C-Term)

N° du produit ABIN7453565

L’anticorps anti-PKD2 Polyclonal Lapin est utilisé pour la détection de PKD2 dans des échantillons de Humain. Il a été validé pour WB, IP et IHC (fp).

Aperçu rapide pour PKD2 anticorps (C-Term) (ABIN7453565)

Antigène: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKD2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-PKD2 anticorps

Épitope: C-Term

Fonction: Rabbit anti-PKD2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 825 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:200 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PKD2

Antigène: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Autre désignation: PKD2

Sujet: Background: PKD2 is a member of the protein kinase D (PKD) family of serine/threonine protein kinases that belongs to a subfamily of the calcium-calmodulin kinase-like superfamily. PKD2 and its family members are activated by phorbol esters and diacylglycerol generated by PKC activation. PKD2 has been demonstrated to play a role in IL-2 promoter regulation as well as IL-8 production. PKD2 may also be involved in the regulation of trans-golgi network trafficking.

ID gène: 25865

NCBI Accession: NP_057541

UniProt: Q9BZL6

Pathways: cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity