CHD8 anticorps (AA 325-350)

N° du produit ABIN7453579

Cet anticorps Lapin Polyclonal détecte spécifiquement CHD8 dans WB, IP et IHC (fp). Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour CHD8 anticorps (AA 325-350) (ABIN7453579)

Antigène: CHD8 (Chromodomain Helicase DNA Binding Protein 8 (CHD8))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHD8 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-CHD8 anticorps

Épitope: AA 325-350

Fonction: Rabbit anti-CHD8 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 325 and 350

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CHD8

Antigène: CHD8 (Chromodomain Helicase DNA Binding Protein 8 (CHD8))

Autre désignation: CHD8

Sujet: Background: CHD8 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD8 has been reported to interact with duplin, a protein involved in the wnt signaling pathway, and CTCF, a protein involved in heterochromatin formation.

ID gène: 57680

NCBI Accession: NP_065971

UniProt: Q9HCK8

Pathways: Chromatin Binding