FHL2 anticorps (C-Term)

N° du produit ABIN7453598

L’anticorps Lapin Polyclonal anti-FHL2 a été validé pour WB, IP et IHC (fp). Il convient pour détecter FHL2 dans des échantillons de Humain et Souris.

Aperçu rapide pour FHL2 anticorps (C-Term) (ABIN7453598)

Antigène: FHL2 (Four and A Half LIM Domains 2 (FHL2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FHL2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-FHL2 anticorps

Épitope: C-Term

Fonction: Rabbit anti-FHL2 Antibody, Affinity Purified

Homologie: Rat,Bovine

Purification: Affinity Purified

Immunogène: between AA 225 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 to 1:5,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur FHL2

Antigène: FHL2 (Four and A Half LIM Domains 2 (FHL2))

Autre désignation: FHL2

Sujet: Background: FHL2 is a member of the four-and-a-half-LIM-domain protein family which consists of FHL1, FHL2, FHL3, FHL4, and ACT. The LIM domain is a cysteine-rich motif that mediates protein-protein interactions. FHL2 has been shown to function as a transcriptional cofactor and through its LIM domains, interact with a variety of factors which include the androgen receptor, CREB, AP-1, Runx3, SRF, FOXO1, BRCA1 and the HPV-16 E7 oncoprotein. FHL2 has been demonstrated to play an important role in heart and bone development and may influence cancer cell growth.

ID gène: 2274

NCBI Accession: NP_963849

UniProt: Q14192

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha