DACH1 anticorps (AA 740-760)

N° du produit ABIN7453627

Cet anticorps Lapin Polyclonal détecte spécifiquement DACH1 dans WB, IP et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour DACH1 anticorps (AA 740-760) (ABIN7453627)

Antigène: DACH1 (Dachshund 1 (DACH1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DACH1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-DACH1 anticorps

Épitope: AA 740-760

Fonction: Rabbit anti-DACH1 Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: between AA 740 and 760

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur DACH1

Antigène: DACH1 (Dachshund 1 (DACH1))

Autre désignation: DACH1

Sujet: Background: Dachshund homolog 1 (Dach1) is a transcription factor that is involved in regulation of organogenesis. Dach1 seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Dach1 seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter (by similarity) [taken from the Universal Protein Resource (UniProt) Q9UI36].

ID gène: 1602

UniProt: Q9UI36

Pathways: Feeding Behaviour