Apoptosis Inhibitor 5 anticorps (AA 1-50)

N° du produit ABIN7453657

Cet anticorps Lapin Polyclonal détecte spécifiquement Apoptosis Inhibitor 5 dans WB, IP et IHC (fp). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Apoptosis Inhibitor 5 anticorps (AA 1-50) (ABIN7453657)

Antigène: Apoptosis Inhibitor 5 (API5)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Apoptosis Inhibitor 5 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-Apoptosis Inhibitor 5 anticorps

Épitope: AA 1-50

Fonction: Rabbit anti-API5 Antibody, Affinity Purified

Homologie: X. laevis,Chicken,Orangutan

Purification: Affinity Purified

Immunogène: between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Apoptosis Inhibitor 5

Antigène: Apoptosis Inhibitor 5 (API5)

Autre désignation: API5

Sujet: Background: API5 (apoptosis inhibitor 5) is an antiapoptotic factor that may have a role in protein assembly. API5 negatively regulates ACIN1. By binding to ACIN1, API5 suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. API5 is also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.

ID gène: 8539

NCBI Accession: XP_508375

UniProt: Q9BZZ5

Pathways: Growth Factor Binding