EYA3 anticorps (AA 1-30)

N° du produit ABIN7453703

L’anticorps Lapin Polyclonal anti-EYA3 a été validé pour WB, IP et IHC (fp). Il convient pour détecter EYA3 dans des échantillons de Humain.

Aperçu rapide pour EYA3 anticorps (AA 1-30) (ABIN7453703)

Antigène: EYA3 (Eyes Absent Homolog 3 (EYA3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EYA3 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-EYA3 anticorps

Épitope: AA 1-30

Fonction: Rabbit anti-EYA3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1 and 30

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur EYA3

Antigène: EYA3 (Eyes Absent Homolog 3 (EYA3))

Autre désignation: EYA3

Sujet: Background: EYA3 (eyes absent homolog 3) functions as a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). EYA3 promotes efficient DNA repair by dephosphorylating H2AX and promoting the recruitment of DNA repair complexes containing MDC1. EYA3 coactivates SIX1. Together with SIX1 and DACH2 EYA3 seems to be involved in myogenesis. EYA3 may be involved in development of the eye [taken from the Universal Protein Resource (UniProt) Q99504].

ID gène: 2140

NCBI Accession: NP_001981

UniProt: Q99504

Pathways: Positive Regulation of Response to DNA Damage Stimulus