SAFB anticorps (C-Term)

N° du produit ABIN7453777

Cet anticorps Lapin Polyclonal détecte spécifiquement SAFB dans WB, IP et IHC (fp). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour SAFB anticorps (C-Term) (ABIN7453777)

Antigène: SAFB (Scaffold Attachment Factor B (SAFB))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAFB est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-SAFB anticorps

Épitope: C-Term

Fonction: Rabbit anti-SAFB1 Antibody, Affinity Purified

Homologie: Orangutan

Purification: Affinity Purified

Immunogène: between AA 875 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SAFB

Antigène: SAFB (Scaffold Attachment Factor B (SAFB))

Autre désignation: SAFB1

Sujet: Background: Scaffold attachment factor B1 (SAFB1) is a chromatin associated protein that interacts with DNA elements termed S/MARs (scaffold or matrix attachment regions) but is not part of the nuclear matrix. SAFB1 is ubiquitously expressed and appears to be a multifunctional protein involved in chromatin organization, mRNA processing and transcriptional regulation. SAFB1 has been demonstrated to interact with and function as a corepressor with many nuclear receptors such as estrogen receptor-alpha, PPAR-gamma, and FXR-alpha.

ID gène: 6294

NCBI Accession: NP_002958

UniProt: Q15424

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway