SF3A1 anticorps (AA 500-550)

N° du produit ABIN7453781

L’anticorps Lapin Polyclonal anti-SF3A1 a été validé pour WB, IP et IHC (fp). Il convient pour détecter SF3A1 dans des échantillons de Humain.

Aperçu rapide pour SF3A1 anticorps (AA 500-550) (ABIN7453781)

Antigène: SF3A1 (Splicing Factor 3a, Subunit 1 (SF3A1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SF3A1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-SF3A1 anticorps

Épitope: AA 500-550

Fonction: Rabbit anti-SF3a120/SAP114 Antibody, Affinity Purified

Homologie: Mouse,Bovine

Purification: Affinity Purified

Immunogène: between AA 500 and 550

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SF3A1

Antigène: SF3A1 (Splicing Factor 3a, Subunit 1 (SF3A1))

Autre désignation: SF3a120/SAP114

Sujet: Background: SF3a120/SAP114 is a 120 kDa subunit of the heterotrimeric splicing factor 3a (SF3A) protein complex. SF3A along with SF3B and a 12S RNA subunit are components of the 17S U2 small nuclear ribonucleoprotein complex (U2 snRNP) involved in pre-mRNA splicing. SF3a120/SAP114 bears two SURP motif repeats and one ubiquitin-like domain. SURP motifs are found among proteins involved in regulated mRNA splicing. The SURP motifs along with the ubiquitin-like domain of SF3a120/SAP114 appear to function in the heterotrimeric formation between the 120, 60 and 66 kDa subunits.

ID gène: 10291

NCBI Accession: NP_005868

UniProt: Q15459

Pathways: Ribonucleoprotein Complex Subunit Organization