ORC3 anticorps (AA 325-375)

N° du produit ABIN7453837

Cet anticorps Lapin Polyclonal détecte spécifiquement ORC3 dans WB, IP et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour ORC3 anticorps (AA 325-375) (ABIN7453837)

Antigène: ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ORC3 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-ORC3 anticorps

Épitope: AA 325-375

Fonction: Rabbit anti-ORC3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 325 and 375

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur ORC3

Antigène: ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))

Autre désignation: ORC3

Sujet: Background: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. ORC3 is also known as ORC3L and is a subunit of the human ORC complex. ORC3L forms a core complex with ORC2L, -4L, and -5L [taken from NCBI Entrez Gene (GeneID: 23595)].

ID gène: 23595

NCBI Accession: NP_036513

UniProt: Q9UBD5

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Feeding Behaviour, Synthesis of DNA