TOP2B anticorps (AA 1475-1525)

N° du produit ABIN7453888

Cet anticorps Lapin Polyclonal détecte spécifiquement TOP2B dans WB, IP et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour TOP2B anticorps (AA 1475-1525) (ABIN7453888)

Antigène: TOP2B (Topoisomerase (DNA) II beta 180kDa (TOP2B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOP2B est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-TOP2B anticorps

Épitope: AA 1475-1525

Fonction: Rabbit anti-Topo II Beta Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1475 and 1525

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur TOP2B

Antigène: TOP2B (Topoisomerase (DNA) II beta 180kDa (TOP2B))

Autre désignation: Topo II Beta

Sujet: Background: Topoisomerases regulate topological states of DNA and are divided into type I and type II enzymes. Type II topoisomerases make double stranded breaks in DNA and allow the passage of another duplex DNA across the break to achieve unknotting of entangled DNA. Topo II beta is one of two described isoforms that are likely products of a gene duplication event. TopoII beta is also described to be involved in chromosome condensation, chromatid separation, and the relief of supercoil stress.

ID gène: 7155

NCBI Accession: NP_001059

UniProt: Q02880