Recombinant Liver Arginase anticorps (AA 1-322)

N° du produit ABIN7453894

Cet anticorps Lapin Monoclonal détecte spécifiquement Liver Arginase dans WB, IHC (fp) et IP. Il présente une réactivité envers Souris.

Aperçu rapide pour Recombinant Liver Arginase anticorps (AA 1-322) (ABIN7453894)

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Liver Arginase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)

Clone: BLR161J

Détail du produit anti-Liver Arginase anticorps

Épitope: AA 1-322

Fonction: Rabbit anti-Arginase 1 Recombinant Monoclonal Antibody [BLR161J]

Immunogène: residues 1-322 (FL)

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 20 μL/1 mg lysate

WB: 01:01,00

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Liver Arginase

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Autre désignation: Arginase 1

Sujet: Background: Arginase1 is a key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively, the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys. Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.  [taken from the Universal Protein Resource (UniProt) P05089].

ID gène: 11846

NCBI Accession: NP_031508

UniProt: Q61176

Pathways: Cellular Response to Molecule of Bacterial Origin