Recombinant ZEB2 anticorps (AA 1164-1214)
Aperçu rapide pour Recombinant ZEB2 anticorps (AA 1164-1214) (ABIN7453993)
Antigène
Voir toutes ZEB2 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1164-1214
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Fonction
- Rabbit anti-ZEB2/SIP Recombinant Monoclonal Antibody [BLR115H]
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Immunogène
- between AA 1164 and 1214 (C-term)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))
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Autre désignation
- ZEB2/SIP
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Sujet
- Background: Smad interacting protein 1 (SIP1) is a transcriptional inhibitor that binds to the DNA sequence, 5'-CACCT-3', in different promoters. SIP1 has been shown to repress the transcription of E-cadherin. Defects in the gene which encodes for SIP1, ZEB2, are the cause of Hirschsprung disease-mental retardation syndrome (Hirschsprung disease) also known as Mowat-Wilson syndrome (MWS). Hirschsprung disease is a rare autosomal dominant complex developmental disorder [taken from the Universal Protein Resource (UniProt) O60315].
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ID gène
- 9839
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NCBI Accession
- NP_055610
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UniProt
- O60315
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Pathways
- Tube Formation
Antigène
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