PELP1 anticorps (AA 25-75)
Aperçu rapide pour PELP1 anticorps (AA 25-75) (ABIN7454378)
Antigène
Voir toutes PELP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 25-75
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Fonction
- Rabbit anti-PELP1/MNAR Antibody, Affinity Purified
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Homologie
- Monkey
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Purification
- Affinity Purified
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Immunogène
- between AA 25 and 75
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Isotype
- IgG
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Indications d'application
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-PELP1/MNAR antibody A300-180A.
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- PELP1 (Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1))
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Autre désignation
- PELP1/MNAR
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Sujet
- Background: PELP1/MNAR was identified as an SH2 domain interacting protein that interacts with Lck, c-Src, and other members of the Src kinase family. PELP1/MNAR appears to function as a general coregulator and interacts with multiple nuclear receptors and transcription factors. PELP1/MNAR has also been shown to participate in nongenomic signaling via an association with a multiprotein complex, the ""signalsome"" involving ERalpha, Src kinase, PI3K, SHC, and G-proteins. As a transcriptional coregulator and signaling protein, PELP/MNAR mediates a variety of cellular functions such as cell proliferation, apoptosis, differentiation, oncogenesis and metastasis.
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ID gène
- 27043
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UniProt
- Q8IZL8
Antigène
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