CHD3 anticorps (AA 1950-2000)

N° du produit ABIN7454393

Cet anticorps anti-CHD3 est un anticorps Lapin Polyclonal détectant CHD3 dans IP et IHC (fp). Adapté pour Humain et Souris.

Aperçu rapide pour CHD3 anticorps (AA 1950-2000) (ABIN7454393)

Antigène: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHD3 est non-conjugé

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-CHD3 anticorps

Épitope: AA 1950-2000

Fonction: Rabbit anti-CHD3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1950 and 2000

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-CHD3 antibody A301-219A.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CHD3

Antigène: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Autre désignation: CHD3

Sujet: Background: CHD3 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD3 is a key component of the NuRD (nucleosomal remodeling) complex and directly interacts with histone deacetylases 1 and 2, ATR, and TRIM 27. Studies in several species suggest a role for CHD3 in the repression of developmental genes.

ID gène: 1107

NCBI Accession: NP_001005273

UniProt: Q12873