RANGAP1 anticorps (AA 400-450)

N° du produit ABIN7454428

L’anticorps Lapin Polyclonal anti-RANGAP1 a été validé pour IP et IHC (fp). Il convient pour détecter RANGAP1 dans des échantillons de Humain.

Aperçu rapide pour RANGAP1 anticorps (AA 400-450) (ABIN7454428)

Antigène: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RANGAP1 est non-conjugé

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-RANGAP1 anticorps

Épitope: AA 400-450

Fonction: Rabbit anti-RanGAP1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 400 and 450

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-RanGAP1 antibody A302-026A.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur RANGAP1

Antigène: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Autre désignation: RanGAP1

Sujet: Background: The regulation of GTPase activity is achieved via activators called GEFs (guanine-nucleotide exchange factors) and inactivators called GAPs (GTPase-activating proteins). Ran-specific GTPase-activating protein 1 (RanGAP1) induces the GTPase activity of the RAN small GTPase. The Ran GTPase plays a role in spatial information and nucleocytoplasmic transport. RanGAP1 is the antagonist of the GEF RCC1 which keeps RAN in the active GTP-bound state.

ID gène: 5905

NCBI Accession: NP_002874

UniProt: P46060

Pathways: M Phase, Protein targeting to Nucleus