ZEB2 anticorps (AA 750-800)

N° du produit ABIN7454452

L’anticorps Lapin Polyclonal anti-ZEB2 a été validé pour IP et IHC (fp). Il convient pour détecter ZEB2 dans des échantillons de Humain.

Aperçu rapide pour ZEB2 anticorps (AA 750-800) (ABIN7454452)

Antigène: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZEB2 est non-conjugé

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-ZEB2 anticorps

Épitope: AA 750-800

Fonction: Rabbit anti-ZEB2/SIP Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 750 and 800

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-ZEB2/SIP antibody A302-474A.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur ZEB2

Antigène: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Autre désignation: ZEB2/SIP

Sujet: Background: Smad interacting protein 1 (SIP1) is a transcriptional inhibitor that binds to the DNA sequence, 5'-CACCT-3', in different promoters. SIP1 has been shown to repress the transcription of E-cadherin. Defects in the gene which encodes for SIP1, ZEB2, are the cause of Hirschsprung disease-mental retardation syndrome (Hirschsprung disease) also known as Mowat-Wilson syndrome (MWS). Hirschsprung disease is a rare autosomal dominant complex developmental disorder [taken from the Universal Protein Resource (UniProt) O60315].

ID gène: 9839

NCBI Accession: NP_055610

UniProt: O60315

Pathways: Tube Formation