PUF60 anticorps (AA 509-559)

N° du produit ABIN7454555

Cet anticorps anti-PUF60 est un anticorps Lapin Polyclonal détectant PUF60 dans WB et IHC (fp). Adapté pour Humain et Souris.

Aperçu rapide pour PUF60 anticorps (AA 509-559) (ABIN7454555)

Antigène: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PUF60 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-PUF60 anticorps

Épitope: AA 509-559

Fonction: Rabbit anti-PUF60 Antibody, Affinity Purified

Homologie: Rat,Bovine,Orangutan

Purification: Affinity Purified

Immunogène: between AA 509 and 559

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PUF60

Antigène: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Autre désignation: PUF60

Sujet: Background: Poly-U binding splicing factor 60KDa (PUF60) is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. PUF60 is implicated in the xeroderma pigmentosum disorder [taken from NCBI Entrez Gene (Gene ID: 22827)].

ID gène: 22827

NCBI Accession: NP_510965

UniProt: Q9UHX1