PSMA2 anticorps (AA 184-234)

N° du produit ABIN7454564

Cet anticorps anti-PSMA2 est un anticorps Lapin Polyclonal détectant PSMA2 dans WB et IHC (fp). Adapté pour Humain et Souris.

Aperçu rapide pour PSMA2 anticorps (AA 184-234) (ABIN7454564)

Antigène: PSMA2 (Proteasome Subunit alpha 2 (PSMA2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMA2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-PSMA2 anticorps

Épitope: AA 184-234

Fonction: Rabbit anti-PSMA2 Antibody, Affinity Purified

Homologie: Bovine

Purification: Affinity Purified

Immunogène: Between AA 184 and 234

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PSMA2

Antigène: PSMA2 (Proteasome Subunit alpha 2 (PSMA2))

Autre désignation: PSMA2

Sujet: Background: Proteasome (prosome, macropain) subunit, alpha type, 2 (PSMA2) is a component of the proteasome, a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA2 is a member of the peptidase T1A family, that is a 20S core alpha subunit [taken from NCBI Entrez Gene (Gene ID: 5683)].

ID gène: 5683

NCBI Accession: NP_002778

UniProt: P25787

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA