CDK11 anticorps (C-Term)

N° du produit ABIN7454610

Cet anticorps Lapin Polyclonal détecte spécifiquement CDK11 dans WB, IP et IHC (fp). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CDK11 anticorps (C-Term) (ABIN7454610)

Antigène: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK11 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-CDK11 anticorps

Épitope: C-Term

Fonction: Rabbit anti-CDK11 Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: between AA 730 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CDK11

Antigène: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Autre désignation: CDK11

Sujet: Background: CDK11 is a member of the p34Cdc2 protein kinase family and is involved in cell cycle progression, apoptosis, and tumorigenesis. Many isoforms of CDK11 have been isolated. The p58 isoform has been shown to interact with cyclin D3 and to play an important role in G2/M phase progression. The p110 isoforms have been demonstrated to interact with the RNA-binding proteins RNPS1, RNA polymerase II, and many elongation factors, indicating a role in RNA metabolism in proliferating cells.

ID gène: 728642

NCBI Accession: NP_001300825

UniProt: Q9UQ88

Pathways: Regulation of Lipid Metabolism by PPARalpha, M Phase