PARP10 anticorps (AA 300-350)

N° du produit ABIN7454656

Détail du produit anti-PARP10 anticorps

Antigène: PARP10 (Poly (ADP-Ribose) Polymerase Family, Member 10 (PARP10))

Épitope: AA 300-350

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP10 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-PARP10 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 300 and 350

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000: 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PARP10

Antigène: PARP10 (Poly (ADP-Ribose) Polymerase Family, Member 10 (PARP10))

Autre désignation: PARP10 (PARP10 Produits)

Synonymes: anticorps ARTD10, anticorps PARP10, anticorps poly(ADP-ribose) polymerase family member 10, anticorps poly (ADP-ribose) polymerase family, member 10, anticorps PARP10, anticorps Parp10

Sujet: Background: PARP10 is a member of the poly(ADP-ribose) polymerase (PARP) family involved in a variety of processes which includes DNA metabolism, the DNA damage response, transcription and the maintenance of genomic stability. Although each member of the PARP family exhibits poly(ADP-ribose) polymerase activity which catalyzes the attachment of ADP-ribose units from NAD+ to substrate proteins, the endogenous substrates of many of the family members, including PARP10, remain to be identified. Recent studies have shown that PARP10 is localized to the nucleoli and associates with RNA polymerase II. PARP10 is a substrate of and is activated by CDK2 and may serve an important function in cell proliferation.

ID gène: 84875

NCBI Accession: NP_116178

UniProt: Q53GL7