General Transcription Factor 3C Polypeptide 3 (GTF3C3) (AA 475-525) anticorps

N° du produit ABIN7454731

L’anticorps anti-General Transcription Factor 3C Polypeptide 3 Polyclonal Lapin est utilisé pour la détection de General Transcription Factor 3C Polypeptide 3 dans des échantillons de Humain. Il a été validé pour IP, IHC (fp) et WB.

Aperçu rapide pour General Transcription Factor 3C Polypeptide 3 (GTF3C3) (AA 475-525) anticorps (ABIN7454731)

Antigène: General Transcription Factor 3C Polypeptide 3 (GTF3C3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Western Blotting (WB)

Détail du produit

Épitope: AA 475-525

Fonction: Rabbit anti-GTF3C3/TFIIIC102 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 475 and 525

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détail du antigène

Antigène: General Transcription Factor 3C Polypeptide 3 (GTF3C3)

Autre désignation: GTF3C3/TFIIIC102

Sujet: Background: General transcription factor 3C polypeptide 3 (GTF3C3/TFIIIC102) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C3/TFIIIC102 appears to be important for stable complex formation and recruitment of RNA polymerase III by interacting with TFIIIB90, TBP, and TFIIIC63. GTF3C3/TFIIIC102 has been shown to also interact with DEDD and FLAME-3 proteins. This interaction may function to translocate GTF3C3/TFIIIC102 to the nucleus and regulate TFIIIC activity.

ID gène: 9330

NCBI Accession: NP_036218

UniProt: Q9Y5Q9