FKBP4 anticorps (AA 400-440)

N° du produit ABIN7454750

Cet anticorps anti-FKBP4 est un anticorps Lapin Polyclonal détectant FKBP4 dans WB, IP et IHC (fp). Adapté pour Humain.

Aperçu rapide pour FKBP4 anticorps (AA 400-440) (ABIN7454750)

Antigène: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP4 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-FKBP4 anticorps

Épitope: AA 400-440

Fonction: Rabbit anti-FKBP4/FKBP52 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 400 and 440

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur FKBP4

Antigène: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Autre désignation: FKBP4/FKBP52

Sujet: Background: FKBP4/FKBP52 is an immunophilin and target of FK506, a macrolide immunosuppressive drug derived from Streptomyces tsukubaensis. Like other FK506 binding proteins, FKBP52 exhibits peptidyl-prolyl cis-trans isomerase activity, but does not appear to mediate the immunosuppressive activities of FK506. The most studied role of FKBP4/FKBP52 surrounds its involvement in the regulation of steroid receptor signaling. In association with the molecular chaperone Hsp90, FKBP4/FKBP52 is able to influence steroid-hormone binding affinity and transcriptional activity.

ID gène: 2288

NCBI Accession: NP_002005

UniProt: Q02790

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway