EEA1 anticorps (AA 100-150)

N° du produit ABIN7454791

L’anticorps Lapin Polyclonal anti-EEA1 a été validé pour WB, IP et IHC (fp). Il convient pour détecter EEA1 dans des échantillons de Humain.

Aperçu rapide pour EEA1 anticorps (AA 100-150) (ABIN7454791)

Antigène: EEA1 (Early Endosome Antigen 1 (EEA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EEA1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-EEA1 anticorps

Épitope: AA 100-150

Fonction: Rabbit anti-EEA1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 100 and 150

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:200 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur EEA1

Antigène: EEA1 (Early Endosome Antigen 1 (EEA1))

Autre désignation: EEA1

Sujet: Background: Early endosomal autoantigen 1 (EEA1) bears an FYVE (Fab1p-YOPB-Vps27p-EEA1) domain which is an approximately 80 amino acid double-zinc binding motif that binds to PtdIns(3)P (phosphatidylinositol 3-phosphate). The FYVE domain is found in proteins involved in intracellular signaling, membrane trafficking, and cytoskeletal rearrangement. EEA1 binds to early endosomal membranes that contain PtdIns(3)P and plays a role in the docking and fusion of early endosomes.

ID gène: 8411

NCBI Accession: NP_003557

UniProt: Q15075

Pathways: Toll-Like Receptors Cascades