CAMKK2 anticorps (AA 538-588)

N° du produit ABIN7455000

Cet anticorps Lapin Polyclonal détecte spécifiquement CAMKK2 dans WB, IP et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour CAMKK2 anticorps (AA 538-588) (ABIN7455000)

Antigène: CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAMKK2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-CAMKK2 anticorps

Épitope: AA 538-588

Fonction: Rabbit anti-CaMKK2 Antibody, Affinity Purified

Homologie: Rat

Purification: Affinity Purified

Immunogène: Between AA 538 and 588

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:500 - 1:2,500

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CAMKK2

Antigène: CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

Autre désignation: CaMKK2

Sujet: Background: Calcium/calmodulin-dependent protein kinase kinase 2 belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of the CAMKK2 gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation [taken from NCBI Entrez Gene (Gene ID: 10645)].

ID gène: 10645

NCBI Accession: NP_006540

UniProt: Q96RR4

Pathways: AMPK Signaling