DYNC1I2 anticorps (AA 588-638)

N° du produit ABIN7455046

L’anticorps anti-DYNC1I2 Polyclonal Lapin est utilisé pour la détection de DYNC1I2 dans des échantillons de Humain et Souris. Il a été validé pour WB, IHC (fp) et IP.

Aperçu rapide pour DYNC1I2 anticorps (AA 588-638) (ABIN7455046)

Antigène: DYNC1I2 (Dynein, Cytoplasmic 1, Intermediate Chain 2 (DYNC1I2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DYNC1I2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)

Détail du produit anti-DYNC1I2 anticorps

Épitope: AA 588-638

Fonction: Rabbit anti-DYNC1I2 Antibody, Affinity Purified

Homologie: Rat,Bovine,Orangutan

Purification: Affinity Purified

Immunogène: Between AA 588 and 638

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur DYNC1I2

Antigène: DYNC1I2 (Dynein, Cytoplasmic 1, Intermediate Chain 2 (DYNC1I2))

Autre désignation: DYNC1I2

Sujet: Background: Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2) acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. DYNC1I2 is involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes [taken from the Universal Protein Resource (UniProt) Q13409].

ID gène: 1781

NCBI Accession: NP_001369

UniProt: Q13409

Pathways: M Phase