PLAU anticorps
Aperçu rapide pour PLAU anticorps (ABIN7490722)
Antigène
Voir toutes PLAU AnticorpsFragment
Reactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Rabbit/Human Fc chimeric IgG1
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Isotype
- IgG1
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Indications d'application
- Flow Cyt 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Date de péremption
- 12 months
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- PLAU (Plasminogen Activator, Urokinase (PLAU))
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Autre désignation
- UPA
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Sujet
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ATF, BDPLT5, QPD, u-PA, UPA, URK,
Description: This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. -
UniProt
- P00749
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
Antigène
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