FOXC1 anticorps (AA 101-200)

N° du produit ABIN719291

L’anticorps Lapin Polyclonal anti-FOXC1 a été validé pour WB, ELISA, FACS, IHC (p), IF (cc), IF (p) et IHC (fro). Il convient pour détecter FOXC1 dans des échantillons de Humain, Souris, Rat et Chévre.

Aperçu rapide pour FOXC1 anticorps (AA 101-200) (ABIN719291)

Antigène: FOXC1 (Forkhead Box C1 (FOXC1))

Reactivité: Humain, Souris, Rat, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXC1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-FOXC1 anticorps

Épitope: AA 101-200

Réactivité croisée: Chévre, Humain, Souris, Rat

Homologie: Dog,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FOXC1/FREAC3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur FOXC1

Antigène: FOXC1 (Forkhead Box C1 (FOXC1))

Autre désignation: FREAC3

Sujet:

Synonyms: ARA, FKH L7, FKHL 7, FKHL7, Forkhead Drosophila like 7, Forkhead, forkhead box C1, Forkhead box protein C1,Forkhead drosophila homolog like 7, Forkhead like 7, Forkhead related activator 3, Forkhead related protein FKHL7, Forkhead related transcription factor 3, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3, FOX C1, FOXC 1, FOXC1, FOXC1_HUMAN, FREAC 3,FREAC-3, FREAC3, homolog-like 7, IGDA, IHG 1, IHG1, IRID 1, IRID1, Iridogoniodysgenesis type 1, Myeloid factor delta.

Background: Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees.Involvement in disease, Defects in FOXC1 are the cause of Axenfeld-Rieger syndrome type 3 (RIEG3), also known as Axenfeld-Rieger syndrome (ARS) or Axenfeld syndrome or Axenfeld anomaly. It is characterized by posterior corneal embryotoxon, prominent Schwalbe line and iris adhesion to the Schwalbe line. Other features may be hypertelorism (wide spacing of the eyes), hypoplasia of the malar bones, congenital absence of some teeth and mental retardation. When associated with tooth anomalies, the disorder is known as Rieger syndrome. Glaucoma is a progressive blinding condition that occurs in approximately half of patients with Axenfeld-Rieger malformations.

ID gène: 2296

Pathways: Chromatin Binding, Glycosaminoglycan Metabolic Process